Article
Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses.
Nature - 18 Mar 1993
Minty A, Chalon P, Derocq J M, Dumont X, Guillemot J C, Kaghad M, Labit C, Leplatois P, Liauzun P, Miloux B
Abstract excerpt
The discovery of new cytokines normally relies on a prior knowledge of at least one of their biological effects, which is used as a criterion either for the purification of the protein or for the isolation of the complementary DNA by expression cloning. However, the redundancy of cytokine activities complicates the discovery of novel cytokines in this way, and the pleiotropic nature of many cytokines means that...
Topics
- Amino Acid Sequence
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- B-Lymphocytes
- Base Sequence
- CD28 Antigens
- DNA
- Gene Library
- Genetic Variation
- Humans
- Inflammation