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Article

Interleukin-13 stimulation of the mediastinal B-cell lymphoma cell line Karpas-1106P induces a phenotype resembling the Hodgkin lymphoma cell line L1236.

Experimental hematology - 1 Feb 2010

Andersson Erik, Schain Frida, Sjöberg Jan, Björkholm Magnus, Claesson Hans-Erik

Abstract excerpt

OBJECTIVE: Primary mediastinal B-cell lymphoma (PMBCL) and Hodgkin lymphoma (HL) share many biological and clinical characteristics supporting a common pathogenetic pathway. Interleukin (IL)-13 has an important pathophysiological role in HL. In this study, we asked the question of whether IL-13 is a major contributor to the observed difference in features of inflammation between HL and PMBCL. MATERIALS AND...

Topics

Arachidonate 15-Lipoxygenase
Calcium
Cell Line, Tumor
Cell Nucleus
Cell Size
Cytokines
Hodgkin Disease
Humans
Inflammation
Interleukin-13
Interleukin-4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukotrienes

Lymphoma, B-Cell

Phenotype

Receptors, Leukotriene

Source

Identifiers

PMID: 19931589
DOI: 10.1016/j.exphem.2009.11.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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