Article
Genetic analysis of murine senile amyloidosis.
Laboratory investigation; a journal of technical methods and pathology - 1 Mar 1993
Naiki H, Higuchi K, Shimada A, Takeda T, Nakakuki K
Abstract excerpt
BACKGROUND: Recent studies have suggested that not only the genotypes of apolipoprotein A-II, the precursor protein of murine senile amyloid fibrils, but also other genetic factors may contribute to the pathogenesis of murine senile amyloidosis. EXPERIMENTAL DESIGN: We investigated the mode of inheritance of murine senile amyloidosis, using 12-month-old and 14-month-old F1, F2 hybrids and backcrosses between...
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