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Article

Linkage of protection against amyloid fibril formation in the mouse to a single, autosomal dominant gene.

The Journal of experimental medicine - 1 Jun 1995

Gonnerman W A, Elliott-Bryant R, Carreras I, Sipe J D, Cathcart E S

Abstract excerpt

Inbred strains of mice provide a model for studies of the pathogenesis of amyloid A (AA) amyloidosis. All susceptible strains of mice described to date codominantly express two serum amyloid A (apoSAA) isoforms, apoSAA1 and apoSAA2, of which only apoSAA2 serves as a precursor for amyloid fibrils. In previous studies, we have shown that the CE/J strain, which produces a single, novel apoSAA isoform, apoSAACE/J, is...

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Identifiers

PMID: 7760010
DOI: 10.1084/jem.181.6.2249
PMCID: PMC2192067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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