Article
Resistance to secondary amyloidosis in A/J mice is not significantly associated with allelic variants linked to the serum amyloid A gene cluster.
Scandinavian journal of immunology - 1 Sept 1994
Butler A, Whitehead A S
Abstract excerpt
We have tested the hypothesis that structural allelic variants of serum amyloid A confer relative resistance to secondary amyloidosis in the A/J mouse. F2 mice, previously generated from amyloid-resistant (A/J) and amyloid-susceptible (C57BL/6J) strains and categorized with respect to amyloid susceptibility, were genotyped by polymerase chain reaction (PCR) amplification of the polymorphic D7Nds5 microsatellite....
Topics
- Alleles
- Amyloidosis
- Animals
- Base Sequence
- DNA, Satellite
- Genes
- Genetic Linkage
- Genetic Variation
- Humans
- Immunity, Innate
- Mice
- Mice, Inbred C57BL
