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Persistence of virulent Leishmania major in murine cutaneous leishmaniasis: a possible hazard for the host

1 Jan 1993

Abstract excerpt

The persistence of Leishmania major parasites in mice resistant to infection was investigated by the polymerase chain reaction and in vitro culture methods. Parasite-specific DNA was detected in the lymph nodes, spleens, bone marrow, and livers of C57BL/6 mice 1 year after their recovery from infection. Live parasites were also recovered from these tissues (except liver tissues) and were used to establish in...

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PMID: 8093358
DOI: 10.1128/iai.61.1.220-226.1993

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