Purification of alpha-1-antitrypsin monomer by preparative electrophoresis.

doi:10.1136/jcp.47.7.661

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Article

Purification of alpha-1-antitrypsin monomer by preparative electrophoresis.

Journal of clinical pathology - 1 Jul 1994

Spada F, Candiano G, Sergi C, Ghiggeri G M, Callea F, Gusmano R

Abstract excerpt

Alfa-1-antitrypsin (alpha 1AT) was purified by pseudoligand chromatography and preparative electrophoresis from the serum of a patient with alpha 1AT deficiency. The combination of the two techniques yielded a high grade batch of alpha 1AT monomer and this was successfully used to purify the prot...

Topics

Chromatography
Electrophoresis
Humans
Phenotype
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

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