Article
Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.
Proceedings of the National Academy of Sciences of the United States of America - 30 Aug 1994
Näslund J, Schierhorn A, Hellman U, Lannfelt L, Roses A D, Tjernberg L O, Silberring J, Gandy S E, Winblad B, Greengard P
Abstract excerpt
The Alzheimer A beta amyloid peptide (A beta) is the principal proteinaceous component of amyloid associated with Alzheimer disease (AD). We have determined the relative abundance of A beta structural variants present in amyloid from brains of 10 individuals with sporadic AD, 2 individuals with f...
Topics
- Aged
- Aging
- Alzheimer Disease
- Amino Acid Sequence
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Cerebral Cortex
- Female
- Humans
- Male
- Mass Spectrometry
- Molecular Sequence Data
- Mutation