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Article

Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.

Proceedings of the National Academy of Sciences of the United States of America - 30 Aug 1994

Näslund J, Schierhorn A, Hellman U, Lannfelt L, Roses A D, Tjernberg L O, Silberring J, Gandy S E, Winblad B, Greengard P

Abstract excerpt

The Alzheimer A beta amyloid peptide (A beta) is the principal proteinaceous component of amyloid associated with Alzheimer disease (AD). We have determined the relative abundance of A beta structural variants present in amyloid from brains of 10 individuals with sporadic AD, 2 individuals with familial AD carrying specific mutations in the Alzheimer amyloid precursor protein gene, and 5 nondemented elderly...

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Identifiers

PMID: 8078890
DOI: 10.1073/pnas.91.18.8378
PMCID: PMC44609

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