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Clinical Isolates of Measles Virus Use CD46 as a Cellular Receptor

1 May 2000

Abstract excerpt

Laboratory strains of measles viruses (MV), such as Edmonston and Halle, use the complement regulatory protein CD46 as a cell surface receptor. The receptor usage of clinical isolates of MV, however, remains unclear. Receptor usage by primary patient isolates of MV was compared to isolates that had been passaged on a variety of tissue culture cell lines. All of the isolates could infect cells in a CD46-dependent...

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PMID: 10756008
DOI: 10.1128/jvi.74.9.3967-3974.2000

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