Article
Association analysis of the IL2RA gene with alopecia areata in a Chinese population.
Dermatology (Basel, Switzerland) - 1 Jan 2013
Miao Y, Kang Z, Xu F, Qi S, Sheng Y, Han Y, Hu R, Guo X, Yang Q
Abstract excerpt
BACKGROUND: Interleukin-2 receptor subunit alpha (IL2RA) is highly expressed on CD4+CD25+ regulatory T cells and is important for immune homeostasis and the suppression of autoimmune responses. It has been suggested that the single nucleotide polymorphism in IL2RA may affect the pathogenesis of alopecia areata (AA). OBJECTIVE: Our aim was to investigate the link between IL2RA polymorphism and AA in a Chinese...
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