Molecular characterization of the lethal of scute genetic function.

doi:10.1242/dev.118.3.1003

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Molecular characterization of the lethal of scute genetic function.

Development (Cambridge, England) - 1 Jul 1993

Martín-Bermudo M D, González F, Domínguez M, Rodríguez I, Ruiz-Gómez M, Romani S, Modolell J, Jiménez F

Abstract excerpt

The lethal of scute (l'sc) genetic function, which plays an essential role in the early development of the central nervous system of the Drosophila embryo, is localized within the achaete-scute complex (AS-C). Several lines of evidence have suggested that the AS-C T3 transcription unit correspond...

Topics

Amino Acid Sequence
Animals
Animals, Genetically Modified
Base Sequence
Basic Helix-Loop-Helix Transcription Factors
Central Nervous System
Cloning, Molecular
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Insect

Genes, Lethal

Genes, Regulator

Helix-Loop-Helix Motifs

Molecular Sequence Data

Morphogenesis

Phenotype

Source

Open in PubMed

Identifiers

PMID: 8076513
DOI: 10.1242/dev.118.3.1003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8076513-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular characterization of the lethal of scute genetic function.PMID 8076513Read ↗

Distribution and function of the lethal of scute gene product during early neurogenesis in Drosophila.Semantic proximity Read ↗

The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes.Semantic proximity Read ↗

The complex tale of the achaete-scute complex: a paradigmatic case in the analysis of gene organization and function during development.Semantic proximity Read ↗

The genetics of the Drosophila achaete-scute gene complex: a historical appraisal.Semantic proximity Read ↗

Neurogenic genes control gene expression at the transcriptional level in early neurogenesis and in mesectoderm specification.Semantic proximity Read ↗

Recruitment of the proneural gene scute to the Drosophila sex-determination pathway.Semantic proximity Read ↗

Lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis.Semantic proximity Read ↗

The regulation and function of the helix-loop-helix gene, asense, in Drosophila neural precursors.Semantic proximity Read ↗

The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts.Semantic proximity Read ↗

achaete, but not scute, is dispensable for the peripheral nervous system of Drosophila.Semantic proximity Read ↗

Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila.Semantic proximity Read ↗

Control of early neurogenesis of the Drosophila brain by the head gap genes tll, otd, ems, and btd.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.