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Article

Recruitment of the proneural gene scute to the Drosophila sex-determination pathway.

Genetics - 1 Dec 2003

Wrischnik Lisa A, Timmer John R, Megna Lisa A, Cline Thomas W

Abstract excerpt

In flies, scute (sc) works with its paralogs in the achaete-scute-complex (ASC) to direct neuronal development. However, in the family Drosophilidae, sc also acquired a role in the primary event of sex determination, X chromosome counting, by becoming an X chromosome signal element (XSE)-an evolutionary step shown here to have occurred after sc diverged from its closest paralog, achaete (ac). Two...

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Source

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Identifiers

PMID: 14704182
DOI: 10.1093/genetics/165.4.2007
PMCID: PMC1462923

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Source receipt: pubmed, retrieved 7 Sept 2026.

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