Article
Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila.
The EMBO journal - 1 Oct 1991
Cabrera C V, Alonso M C
Abstract excerpt
The achaete-scute complex (AS-C) and the daughterless (da) genes encode helix-loop-helix proteins which have been shown to interact in vivo and to be required for neurogenesis. We show in vitro that heterodimers of three AS-C products with DA bind DNA strongly, whereas DA homodimers bind weakly a...
Topics
- Animals
- Base Sequence
- Basic Helix-Loop-Helix Transcription Factors
- DNA
- DNA, Fungal
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Electrophoresis, Polyacrylamide Gel
- Immunohistochemistry
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Precipitin Tests
- Protein Biosynthesis
- Substrate Specificity
- Transcription Factors
- Transcription, Genetic