No association between c-myc amplification and TP53 mutation in sarcoma tumorigenesis.

doi:10.1016/0165-4608(94)90070-1

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Article

No association between c-myc amplification and TP53 mutation in sarcoma tumorigenesis.

Cancer genetics and cytogenetics - 1 Aug 1994

Castresana J S, Barrios C, Gómez L, Kreicbergs A

Abstract excerpt

Oncogenes and tumor suppressor genes coparticipate in sarcoma tumorigenesis. We tested 43 sarcomas for c-myc amplification by Southern blot and molecular hybridization techniques and TP53 mutations by the polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique and d...

Topics

Base Sequence
Cell Transformation, Neoplastic
Exons
Gene Amplification
Genes, myc
Genes, p53
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Sarcoma

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