Article
No association between c-myc amplification and TP53 mutation in sarcoma tumorigenesis.
Cancer genetics and cytogenetics - 1 Aug 1994
Castresana J S, Barrios C, Gómez L, Kreicbergs A
Abstract excerpt
Oncogenes and tumor suppressor genes coparticipate in sarcoma tumorigenesis. We tested 43 sarcomas for c-myc amplification by Southern blot and molecular hybridization techniques and TP53 mutations by the polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique and direct sequencing of the PCR products. We found eight tumors with c-myc amplification and five different tumors with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.