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Article

Deposition and function of histone H3 variants in Tetrahymena thermophila.

Molecular and cellular biology - 1 Oct 2006

Cui Bowen, Liu Yifan, Gorovsky Martin A

Abstract excerpt

In Tetrahymena, HHT1 and HHT2 genes encode the same major histone H3; HHT3 and HHT4 encode similar minor H3 variants (H3s), H3.3 and H3.4. Green fluorescent protein (GFP)-tagged H3 is deposited onto chromatin through a DNA replication-coupled (RC) pathway. GFP-tagged H3.3 and H3.4 can be deposited both by a transcription-associated, replication-independent (RI) pathway and also weakly by an RC pathway. Although...

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Identifiers

PMID: 16908532
DOI: 10.1128/MCB.01139-06
PMCID: PMC1636873

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