Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage.

Nucleic acids research - 11 Aug 1994

Larminat F, Bohr V A

Abstract excerpt

The human excision repair gene ERCC-1 gene restores normal resistance to UV and mitomycin C in excision repair deficient chinese hamster ovary cells of complementation group 1. To investigate the involvement of the ERCC-1 gene in gene-specific repair of bulky lesions, we have studied the removal of damage induced by the antitumor agent cisplatin in CHO mutant 43-3B cells of group 1, with or without transfection...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cricetinae
Share to DNA
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Damage

Share to DNA Repair

Share to Mutation

Share to Proteins

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 8065913
DOI: 10.1093/nar/22.15.3005
PMCID: PMC310268

Genes

DHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage.PMID 8065913Read ↗

Cisplatin sensitivity/resistance in UV repair-deficient Chinese hamster ovary cells of complementation groups 1 and 3Semantic proximity Read ↗

Cisplatin-induced apoptosis in 43-3B and 27-1 cells defective in nucleotide excision repair.Semantic proximity Read ↗

Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin.Semantic proximity Read ↗

ERCC1 mutations in UV-sensitive Chinese hamster ovary (CHO) cell lines.Semantic proximity Read ↗

Novel Role of Base Excision Repair in Mediating Cisplatin CytotoxicitySemantic proximity Read ↗

Molecular cloning and biological characterization of the human excision repair gene ERCC-3.Semantic proximity Read ↗

ERCC1 expression as a molecular marker of cisplatin resistance in human cervical tumor cellsSemantic proximity Read ↗

Plant homologue of human excision repair gene ERCC1 points to conservation of DNA repair mechanisms.Semantic proximity Read ↗

Nucleotide excision repair proteins and their importance for radiation-enhanced transfection.Semantic proximity Read ↗

Characterization of revertants of the CHO EM9 mutant arising during DNA transfection.Semantic proximity Read ↗

Expression of a splicing variant in the 5'-UTR of the human ERCC1 gene is not cancer related.Semantic proximity Read ↗

Overexpression and activation of the insulin receptor enhances expression of ERCC-1 messenger ribonucleic acid in cultured cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.