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Article

Expression of a splicing variant in the 5'-UTR of the human ERCC1 gene is not cancer related.

Oncogene - 17 Mar 2005

Winter Andrew G, Dorgan Clare, Melton David W

Abstract excerpt

Cisplatin is the most commonly used chemotherapeutic agent in the treatment of ovarian cancer. One of the mechanisms of resistance of ovarian tumours to cisplatin is increased nucleotide excision repair activity, in particular increased levels of the endonuclease ERCC1. Since 30-40% of ovarian cancers develop resistance to cisplatin after treatment and these tumours are usually incurable, ERCC1 expression is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15688021
DOI: 10.1038/sj.onc.1208400

Genes

ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of a splicing variant in the 5'-UTR of the human ERCC1 gene is not cancer related.PMID 15688021Read ↗

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