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Article

Biological amplification of low frequency mutations unravels laboratory culture history of the bio-threat agent Francisella tularensis.

Forensic science international. Genetics - 1 Mar 2020

Dwibedi Chinmay, Larsson Pär, Ahlinder Jon, Lindgren Petter, Myrtennäs Kerstin, Granberg Malin, Larsson Eva, Öhrman Caroline, Sjödin Andreas, Stenberg Per, Forsman Mats, Johansson Anders

Abstract excerpt

Challenges of investigating a suspected bio attack include establishing if microorganisms have been cultured to produce attack material and to identify their source. Addressing both issues, we have investigated genetic variations that emerge during laboratory culturing of the bacterial pathogen Francisella tularensis. Key aims were to identify genetic variations that are characteristic of laboratory culturing and...

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PMID: 31924594
DOI: 10.1016/j.fsigen.2019.102230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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