Article
Ofloxacin induces cytoplasmic respiration-deficient mutants in yeast Saccharomyces cerevisiae.
Current genetics - 1 May 1992
Obernauerová M, Subík J, Ebringer L
Abstract excerpt
Ofloxacin, a new quinolone with potent antibacterial activity, was also found to be effective against yeast. At relatively high concentrations, and at mild alkaline pH, ofloxacin inhibited the growth of yeast cells in medium containing glucose, and prevented growth on glycerol, as carbon and ener...
Topics
- Cell Division
- Cycloheximide
- DNA Topoisomerases, Type I
- DNA, Mitochondrial
- Ethidium
- Glucose
- Glycerol
- Hydrogen-Ion Concentration
- Mutation
- Ofloxacin
- Oxygen Consumption
- Saccharomyces cerevisiae