Article
Isolation and characterization of respiration-deficient mutants from the pathogenic yeast Candida albicans.
Antonie van Leeuwenhoek - 1 Apr 1992
Hatab M A, Whittaker P A
Abstract excerpt
The isolation of several respiration deficient mutants of the pathogenic yeast Candida albicans is described. These show greatly reduced respiration rates, loss of cytochromes aa3 and b, and reduced growth rates. All of the mutants had lost the ability to assimilate a wide range of carbon sources. Ultrastructural studies showed reduced development of mitochondrial cristae in the mutants. The mutants can be...
Topics
- Antimycin A
- Candida albicans
- Carbohydrate Metabolism
- Cyanides
- Cytochrome b Group
- Cytochrome c Group
- Fermentation
- Microscopy, Electron
- Mitochondria
- Mutation
- Oxygen Consumption