Article
Constitutively active receptors as a disease-causing mechanism.
Molecular and cellular endocrinology - 1 Apr 1994
Parma J, Duprez L, Van Sande J, Paschke R, Tonacchera M, Dumont J, Vassart G
Abstract excerpt
Membrane receptors have appeared early in evolution as the means for the unicellular organism to sense its environment. With the emergence of social cellular life in multicellular organisms, membrane receptors have acquired the additional functions of sensing the presence of similar cells (as in...
Topics
- Animals
- Disease
- GTP-Binding Proteins
- Gene Expression Regulation
- Humans
- Mice
- Models, Biological
- Models, Molecular
- Mutation
- Receptors, Cell Surface
- Signal Transduction
