Article
Acetylcholine receptor-reactive T lymphocytes from healthy subjects and myasthenia gravis patients.
Neurology - 1 Aug 1991
Sommer N, Harcourt G C, Willcox N, Beeson D, Newsom-Davis J
Abstract excerpt
Peripheral blood lymphocytes from 23 of 114 (20%) myasthenia gravis (MG) patients showed positive T-cell proliferative responses to native acetylcholine receptor (AChR) purified from the electric fish Torpedo, compared with two of 25 (8%) healthy or other neurologic disease controls. Responsiveness appeared to fluctuate seasonally. Long-term T-cell lines and clones could be selected as readily from the two...
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