Acetylcholine receptor-reactive T lymphocytes from healthy subjects and myasthenia gravis patients.

doi:10.1212/wnl.41.8.1270

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Article

Acetylcholine receptor-reactive T lymphocytes from healthy subjects and myasthenia gravis patients.

Neurology - 1 Aug 1991

Sommer N, Harcourt G C, Willcox N, Beeson D, Newsom-Davis J

Abstract excerpt

Peripheral blood lymphocytes from 23 of 114 (20%) myasthenia gravis (MG) patients showed positive T-cell proliferative responses to native acetylcholine receptor (AChR) purified from the electric fish Torpedo, compared with two of 25 (8%) healthy or other neurologic disease controls. Responsivene...

Topics

Animals
Cell Division
Cell Line
Epitopes
HLA Antigens
Humans
Myasthenia Gravis
Phenotype
Receptors, Cholinergic
Recombinant Proteins
Reference Values
T-Lymphocytes
Time Factors
Torpedo

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