Article
Nuclear congression and membrane fusion: two distinct events in the yeast karyogamy pathway.
The Journal of cell biology - 1 Aug 1994
Kurihara L J, Beh C T, Latterich M, Schekman R, Rose M D
Abstract excerpt
Karyogamy is the process where haploid nuclei fuse to form a diploid nucleus during yeast mating. We devised a novel genetic screen that identified five new karyogamy (KAR) genes and three new cell fusion (FUS) genes. The kar mutants fell into two classes that represent distinct events in the yeast karyogamy pathway. Class I mutations blocked congression of the nuclei due to cytoplasmic microtubule defects. In...
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