Article
Prm3p is a pheromone-induced peripheral nuclear envelope protein required for yeast nuclear fusion.
Molecular biology of the cell - 1 May 2009
Shen Shu, Tobery Cynthia E, Rose Mark D
Abstract excerpt
Nuclear membrane fusion is the last step in the mating pathway of the yeast Saccharomyces cerevisiae. We adapted a bioinformatics approach to identify putative pheromone-induced membrane proteins potentially required for nuclear membrane fusion. One protein, Prm3p, was found to be required for nuclear membrane fusion; disruption of PRM3 caused a strong bilateral defect, in which nuclear congression was completed...
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