Article
Nuclear fusion and genome encounter during yeast zygote formation.
Molecular biology of the cell - 1 Jun 2009
Tartakoff Alan Michael, Jaiswal Purnima
Abstract excerpt
When haploid cells of Saccharomyces cerevisiae are crossed, parental nuclei congress and fuse with each other. To investigate underlying mechanisms, we have developed assays that evaluate the impact of drugs and mutations. Nuclear congression is inhibited by drugs that perturb the actin and tubulin cytoskeletons. Nuclear envelope (NE) fusion consists of at least five steps in which preliminary modifications are...
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