Attachment of Toxoplasma gondii to host cells involves major surface protein, SAG-1 (P30).

doi:10.1006/expr.1994.1054

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Attachment of Toxoplasma gondii to host cells involves major surface protein, SAG-1 (P30).

Experimental parasitology - 1 Aug 1994

Mineo J R, Kasper L H

Abstract excerpt

Previous observations have demonstrated that monoclonal and polyclonal antibodies directed at SAG-1, the major surface protein of Toxoplasma gondii, decreased the number of T. gondii that infected fibroblast monolayers. Direct evaluation of parasite-host cell attachment using glutaraldehyde-fixed human fibroblasts and live tachyzoites was performed to determine whether SAG-1 was a ligand for the host cell...

Topics

Animals
Antibodies, Monoclonal
Antibodies, Protozoan
Antigens, Protozoan
Antigens, Surface
Binding, Competitive
Cell Adhesion
Cells, Cultured
Dose-Response Relationship, Immunologic
Fibroblasts
Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunoglobulin Fab Fragments

Immunoglobulin G

Kinetics

Ligands

Mutation

Protozoan Proteins

Source

Open in PubMed

Identifiers

PMID: 8050521
DOI: 10.1006/expr.1994.1054

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8050521-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Attachment of Toxoplasma gondii to host cells involves major surface protein, SAG-1 (P30).PMID 8050521Read ↗

Toxoplasma gondii uses sulfated proteoglycans for substrate and host cell attachment.Semantic proximity Read ↗

Surface antigens of Toxoplasma gondii: variations on a theme.Semantic proximity Read ↗

Direct enzyme-linked aptamer assay (DELAA) for diagnosis of toxoplasmosis by detection of SAG1 protein in mice and humansSemantic proximity Read ↗

Analysis of host cell binding specificity mediated by the Tp0136 adhesin of the syphilis agent Treponema pallidum subsp. pallidumSemantic proximity Read ↗

Conformationally appropriate expression of the Toxoplasma antigen SAG1 (p30) in CHO cellsSemantic proximity Read ↗

Toxoplasma gondii: stable complementation of sag1 (p30) mutants using SAG1 transfection and fluorescence-activated cell sorting.Semantic proximity Read ↗

The role of surface glycoconjugates in Leishmania midgut attachment examined by competitive binding assays and experimental development in sand flies.Semantic proximity Read ↗

Involvement of host cell heparan sulfate proteoglycan in Trypanosoma cruzi amastigote attachment and invasion.Semantic proximity Read ↗

[Stable green fluorescent protein expression in Toxoplasma gondii mutant].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.