Article
Alternative cell fate choice induced by low-level expression of a regulator of protein phosphatase 2A in the Drosophila peripheral nervous system.
Development (Cambridge, England) - 1 Jun 1994
Shiomi K, Takeichi M, Nishida Y, Nishi Y, Uemura T
Abstract excerpt
The Drosophila gene twins encodes the regulatory B subunit of type 2A protein phosphatase. Here we report that its partial loss-of-function mutations caused abnormal morphogenesis in the adult peripheral nervous system. In wild-type flies, the mechanoreceptor, one major class of sensory organs, is composed of four specialized cells (one neuron and three accessory cells) that are derived from a single precursor...
Topics
- Alleles
- Animals
- Base Sequence
- Cell Differentiation
- DNA Primers
- Drosophila
- Gene Expression
- Genes, Insect
- Molecular Sequence Data
- Peripheral Nervous System
- Phenotype