Article
Mouse rump-white mutation associated with an inversion of chromosome 5.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 1994
Stephenson D A, Lee K H, Nagle D L, Yen C H, Morrow A, Miller D, Chapman V M, Bućan M
Abstract excerpt
The rump-white (Rw) mutation in the mouse was previously mapped as part of a cluster of spotting genes on Chromosome (Chr) 5 that includes the dominant spotting (W) and patch (Ph) loci. Recent studies have shown that the W locus encodes the KIT tyrosine kinase cell surface receptor and that Ph is a deletional mutation encompassing the platelet-derived growth factor receptor alpha subunit (Pdgfra) gene. However,...
Topics
- Animals
- Chromosome Aberrations
- Chromosome Inversion
- Chromosome Mapping
- Genetic Markers
- In Situ Hybridization, Fluorescence
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Mutation