Fine genetic mapping of the Hyp mutation on mouse chromosome X.

doi:10.1006/geno.1996.0103

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Article

Fine genetic mapping of the Hyp mutation on mouse chromosome X.

Genomics - 1 Mar 1996

Du L, Desbarats M, Cornibert S, Malo D, Ecarot B

Abstract excerpt

The hypophosphatemic (Hyp) mouse is the murine homolog of hypophosphatemic vitamin-D-resistant rickets (HYP) in human. Despite extensive investigations in the Hyp mouse, the pathophysiology of this X-linked dominant disorder remains unclear. As a first step toward cloning the Hyp gene, we have ge...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Female
Genetic Linkage
Hypophosphatemia
Male
Mice
Mice, Inbred C57BL
Mutation
Recombination, Genetic
X Chromosome

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