Alzheimer's disease. Clinical molecular genetics.

Article

Alzheimer's disease. Clinical molecular genetics.

Clinics in geriatric medicine - 1 May 1994

Hardy J

Abstract excerpt

The study of the genetics of AD has shown that at least three loci are involved in causing the disease: (1) the APP gene, in which a series of mutations cause the disease to develop in 50- to 60-year-old patients; (2) the ApoE gene in which genetic variability (the E4 allele) is a predisposing fa...

Topics

Alzheimer Disease
Amino Acid Sequence
Humans
Molecular Biology
Molecular Sequence Data
Mutation

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