Article
Positively charged residues influence the degree of SecA dependence in protein translocation across the E. coli inner membrane.
FEBS letters - 27 Jun 1994
Andersson H, von Heijne G
Abstract excerpt
The sec machinery catalyzes the translocation of nascent polypeptide chains across the inner membrane of E. coli, yet some inner membrane proteins depend only weakly or not at all on an intact sec function for membrane insertion even though they have stretches of chain protruding into the periplasmic space. Earlier work has demonstrated that the length of a periplasmic loop correlates with its degree of...
Topics
- Adenosine Triphosphatases
- Amino Acid Sequence
- Azides
- Bacterial Proteins
- Biological Transport
- Cell Membrane
- Electrochemistry
- Escherichia coli
- Escherichia coli Proteins
- Membrane Transport Proteins
- Mutation