Article
Thyroid hormone responsiveness is developmentally regulated in the rat small intestine: a possible role for the alpha-2 receptor variant.
Endocrinology - 1 Aug 1994
Hodin R A, Meng S, Chamberlain S M
Abstract excerpt
Thyroid hormone (T3) alters gene expression through binding to a receptor protein located within the nucleus of target cells. Multiple forms of the T3 receptor (TR) have been identified and are encoded by the alpha and beta c-erbA genes. We have previously found that TR beta-1 is the major receptor form expressed in the adult rat small intestine, although there are also moderate levels of c-erbA alpha-2, a...
Topics
- Alkaline Phosphatase
- Animals
- Genetic Variation
- Intestine, Small
- Lactase
- Microvilli
- RNA, Messenger
- Rats
- Receptors, Thyroid Hormone
- Triiodothyronine
- Weaning