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Organ‐specific effects on target binding due to knockout of thyroid hormone receptor α during Xenopus metamorphosis

18 Nov 2022

Abstract excerpt

Abstract Thyroid hormone (T3) is essential for normal development and metabolism, especially during postembryonic development, a period around birth in mammals when plasma T3 levels reach their peak. T3 functions through two T3 receptors, TRα and TRβ. However, little is known about the tissue‐specific functions of TRs during postembryonic development because of maternal influence and difficulty in manipulation of...

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PMID: 36397722
DOI: 10.1111/dgd.12825

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