Contrasting developmental and tissue-specific expression of alpha and beta thyroid hormone receptor genes.

doi:10.1002/j.1460-2075.1990.tb08270.x

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Article

Contrasting developmental and tissue-specific expression of alpha and beta thyroid hormone receptor genes.

The EMBO journal - 1 May 1990

Forrest D, Sjöberg M, Vennström B

Abstract excerpt

Thyroid hormones and their receptors (TRs) have critical functions in development. Here we show that a chicken TR beta cDNA clone encodes a receptor with a novel, short N-terminal domain. In vitro-expressed TR beta protein bound thyroid hormone with similar affinity as the chicken TR alpha. Compa...

Topics

Amino Acid Sequence
Animals
Base Sequence
Chick Embryo
Chickens
Cloning, Molecular
Genetic Variation
Growth
Molecular Sequence Data
Organ Specificity
Poly A
Proto-Oncogene Proteins
RNA Splicing
RNA, Messenger
Receptors, Thyroid Hormone
Triiodothyronine

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