Article
Contrasting developmental and tissue-specific expression of alpha and beta thyroid hormone receptor genes.
The EMBO journal - 1 May 1990
Forrest D, Sjöberg M, Vennström B
Abstract excerpt
Thyroid hormones and their receptors (TRs) have critical functions in development. Here we show that a chicken TR beta cDNA clone encodes a receptor with a novel, short N-terminal domain. In vitro-expressed TR beta protein bound thyroid hormone with similar affinity as the chicken TR alpha. Comparison of expression of TR alpha and TR beta mRNAs throughout chicken development until 3 weeks post-hatching revealed...
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