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Article

A model for the correlation of mutation rate with GC content and the origin of GC-rich isochores.

Journal of molecular evolution - 1 May 1994

Gu X, Li W H

Abstract excerpt

Based on the biochemical kinetics of DNA replication and mutagenesis, including misincorporation and correction, a model has been developed for studying the relationships among the mutation rate (u), the G+C content of the sequence (f), and the G+C proportion in the nucleotide precursor pool (N). Also a measure for the next-nucleotide effect, called the maximum capacity of the next-nucleotide effect (MC), has...

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PMID: 8028025
DOI: 10.1007/BF00178846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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