Article
[Genetics of Alzheimer's disease].
La Revue de medecine interne - 1 Jan 1996
Hannequin D, Campion D, Brice A, Frebourg T, Martinez M, Clerget-Darpoux F, Agid Y
Abstract excerpt
This review reports the different genetic factors that have been identified either as risk factor for Alzheimer's disease (AD) or directly causing the disease. First are reviewed epidemiological data and biological mechanisms about the apoplipoprotein E gene allele epsilon 4 that is a major risk factor for Alzheimer's disease. The second part describes the mutations responsible for early-onset autosomal dominant...
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