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Article

Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease.

Protein science : a publication of the Protein Society - 1 Mar 1994

Keefe L J, Quirk S, Gittis A, Sondek J, Lattman E E

Abstract excerpt

Alignment of homologous amino acid sequences reveals that insertion mutations are fairly common in evolution. Hitherto, the structural consequences of insertion mutations on the surface and in the interior of proteins of known structures have received little attention. We report here the high-resolution X-ray crystal structures of 2 site-directed insertion mutants of staphylococcal nuclease. The structure of the...

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Identifiers

PMID: 8019410
DOI: 10.1002/pro.5560030303
PMCID: PMC2142708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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