Article
Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease.
Protein science : a publication of the Protein Society - 1 Mar 1994
Keefe L J, Quirk S, Gittis A, Sondek J, Lattman E E
Abstract excerpt
Alignment of homologous amino acid sequences reveals that insertion mutations are fairly common in evolution. Hitherto, the structural consequences of insertion mutations on the surface and in the interior of proteins of known structures have received little attention. We report here the high-res...
Topics
- Amino Acid Sequence
- Binding Sites
- Calcium
- Crystallography, X-Ray
- Hydrogen Bonding
- Micrococcal Nuclease
- Models, Molecular
- Molecular Sequence Data
- Molecular Structure
- Mutagenesis, Insertional
- Mutation
- Protein Conformation
- Protein Structure, Secondary