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Article

Genetic and physiological association of diabetes susceptibility with raised Na+/H+ exchange activity.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 1994

Morahan G, McClive P, Huang D, Little P, Baxter A

Abstract excerpt

Insulin-dependent diabetes mellitus is a multigenic autoimmune disease, for which one of the best animal models is the nonobese diabetic (NOD) mouse strain. In both humans and NOD mice, major histocompatibility complex genes are implicated as risk factors in the disease process. Other susceptibility genes are also involved, and a number have been mapped in the mouse to specific chromosomal locations. To identify...

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Identifiers

PMID: 8016086
DOI: 10.1073/pnas.91.13.5898
PMCID: PMC44104

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