Article
Sibling correlations and segregation analysis of age-related maculopathy: the Beaver Dam Eye Study.
Genetic epidemiology - 1 Jan 1994
Heiba I M, Elston R C, Klein B E, Klein R
Abstract excerpt
Sibling correlations were evaluated and segregation analysis was performed on age-dependent maculopathy scores of the right and left eyes of individuals from 564 families in the Beaver Dam Eye study. There is evidence of significant sibling correlations. The data fit a mixture of two normal distributions, especially after undergoing the Box and Cox power transformation. In each eye, the hypothesis of mendelian...
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