Article
Sibling correlations and segregation analysis of age-related maculopathy: the Beaver Dam Eye Study.
Genetic epidemiology - 1 Jan 1994
Heiba I M, Elston R C, Klein B E, Klein R
Abstract excerpt
Sibling correlations were evaluated and segregation analysis was performed on age-dependent maculopathy scores of the right and left eyes of individuals from 564 families in the Beaver Dam Eye study. There is evidence of significant sibling correlations. The data fit a mixture of two normal distr...
Topics
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Bias
- Chromosome Mapping
- Environment
- Female
- Genes, Dominant
- Genetic Variation
- Humans
- Likelihood Functions
- Macular Degeneration
- Male
- Middle Aged
- Models, Genetic
- Normal Distribution
- Pedigree