Combining two-point genetic linkage analyses using mapping functions.

doi:10.1002/gepi.1370110102

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Article

Combining two-point genetic linkage analyses using mapping functions.

Genetic epidemiology - 1 Jan 1994

Schaid D J, Elston R C

Abstract excerpt

A likelihood ratio statistic is proposed for combining two-point genetic linkage analyses when the two-point analyses are between a trait and a well-defined map of markers. It is assumed that the two-point analyses are independent, as in the case of choosing only the most informative marker per f...

Topics

Bias
Chi-Square Distribution
Chromosome Mapping
Genetic Markers
Genetics, Population
Genotype
Humans
Likelihood Functions
Lod Score
Models, Genetic
Pedigree
Reproducibility of Results

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