Article
Nasal application of the cationic liposome DC-Chol:DOPE does not alter ion transport, lung function or bacterial growth
1 Mar 1994
Abstract excerpt
Liposome-mediated gene transfer is commonly used for in vitro transfection of deoxyribonucleic acid (DNA) into mammalian cells. We and others have recently demonstrated that this can be an effective method for in vivo delivery of plasmid DNA containing the human cystic fibrosis transmembrane conductance regulator (CFTR) gene to mouse models of cystic fibrosis (CF). This suggests that cationic liposomes may be...
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