Article
Nasal airway ion transport and lung function in young people with cystic fibrosis.
American journal of respiratory and critical care medicine - 1 Sept 2003
Wallace Helen L, Barker Pierre M, Southern Kevin W
Abstract excerpt
There is strong evidence that abnormal airway ion transport is the primary defect that initiates the pathophysiology of lung disease in cystic fibrosis (CF). To examine the relationship between airway ion transport abnormality and severity of lung disease, we measured nasal potential difference in 51 young people with CF using a validated modified technique. There was no correlation between any component of the...
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