Nerve growth factor suppresses the tumoral phenotype of human prolactinomas.

doi:10.1159/000185470

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Article

Nerve growth factor suppresses the tumoral phenotype of human prolactinomas.

Hormone research - 1 Jan 1997

Missale C, Sigala S, Fiorentini C, Finardi A, Losa M, Giovanelli M, Spano P

Abstract excerpt

We summarize here our data showing that various phenotypical characteristics distinguish prolactinoma cell lines obtained from responder and nonresponder patients, as defined by their responses to bromocriptine administration. Nonresponder cell lines have a higher degree of malignancy than respon...

Topics

Animals
Bromocriptine
Humans
Mice
Mice, Nude
Neoplasm Transplantation
Nerve Growth Factors
Phenotype
Pituitary Neoplasms
Prolactinoma
Tumor Cells, Cultured

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