Article
Nerve growth factor suppresses the tumoral phenotype of human prolactinomas.
Hormone research - 1 Jan 1997
Missale C, Sigala S, Fiorentini C, Finardi A, Losa M, Giovanelli M, Spano P
Abstract excerpt
We summarize here our data showing that various phenotypical characteristics distinguish prolactinoma cell lines obtained from responder and nonresponder patients, as defined by their responses to bromocriptine administration. Nonresponder cell lines have a higher degree of malignancy than responder cells and do not express D2 receptors for dopamine. Both cell lines express NGF receptors. Exposure of the most...
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