Article
Lymphocyte activation in HIV-1 infection. II. Functional defects of CD28- T cells.
AIDS (London, England) - 1 Apr 1994
Borthwick N J, Bofill M, Gombert W M, Akbar A N, Medina E, Sagawa K, Lipman M C, Johnson M A, Janossy G
Abstract excerpt
OBJECTIVES AND DESIGN: The expression of the accessory molecule CD28 was compared in various populations of T and natural killer (NK) cells from HIV-1-negative and HIV-1-positive individuals and correlated with activation using mitogens in vitro. METHODS: Multiparameter flow cytometric analysis u...
Topics
- Adult
- CD28 Antigens
- Flow Cytometry
- HIV Infections
- HIV-1
- Humans
- Killer Cells, Natural
- Lymphocyte Activation
- Membrane Glycoproteins
- Membrane Proteins
- Perforin
- Phenotype
- Poly(A)-Binding Proteins
- Pore Forming Cytotoxic Proteins
- Proteins
- RNA-Binding Proteins
- T-Cell Intracellular Antigen-1
- T-Lymphocyte Subsets