Article
Major clinical and histopathological characteristics of canine X-linked muscular dystrophy in Japan, CXMDJ.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology - 1 Oct 2005
Shimatsu Yoshiki, Yoshimura Madoka, Yuasa Katsutoshi, Urasawa Nobuyuki, Tomohiro Masayuki, Nakura Masao, Tanigawa Manabu, Nakamura Akinori, Takeda Shin'ichi
Abstract excerpt
Canine X-linked muscular dystrophy (CXMD), which was found in a colony of golden retriever, is caused by a mutation in the dystrophin gene and it is a useful model of Duchenne muscular dystrophy (DMD). To investigate the pathogenesis and to develop therapy of DMD, we have established a beagle-based CXMD colony in Japan (CXMDJ) and examined their phenotypes. The mortality by 3 days of age in the third generation...
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