Article
Interleukin-1 beta regulates human cytotrophoblast metalloproteinase activity and invasion in vitro.
1 Jun 1994
Abstract excerpt
During early human pregnancy, fetal cytotrophoblasts rapidly invade the uterus. This process has many similarities to tumor invasion, except that the extent and the timing of cytotrophoblast invasion are carefully regulated. Therefore, this system is particularly useful for studying mechanisms that regulate invasive processes. Previously, we showed that production and activation of the 92-kDa type IV collagenase...