Expression of Matrix Metalloproteinase-2, -9, and -14, Tissue Inhibitors of Metalloproteinase-1, and Matrix Proteins in Human Placenta During the First Trimester1

Abstract excerpt

Matrix metalloproteinases (MMPs) are implicated in the degradation of extracellular matrix; they play important roles in the invasion of the trophoblast cell into the maternal endometrium during placentation. Previous studies have concentrated on comparison of MMP expression in trophoblast cells between the first and third trimester. But the dynamic expression of MMPs during the first trimester has not been...

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