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Regulation of Trophoblast Invasion by IL‐1β and TGF‐ β1

5 Sept 2002

Abstract excerpt

PROBLEM: To investigate the effect of IL-1beta and TGF-beta1 on trophoblast derived proteases and their inhibitors at the mRNA and protein level for elucidation of the mechanism of trophoblast invasion. METHOD OF STUDY: Trophoblast derived proteases and their inhibitors were localized in human placental villi by immunohistochemistry, their regulation at mRNA and protein levels were studied using RT-PCR and...

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PMID: 12516631
DOI: 10.1034/j.1600-0897.2002.01151.x

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