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Article

Regulated expression of ADAMTS-12 in human trophoblastic cells: a role for ADAMTS-12 in epithelial cell invasion?

PloS one - 11 Apr 2011

Beristain Alexander G, Zhu Hua, Leung Peter C K

Abstract excerpt

Metastatic carcinoma cells exploit the same molecular machinery that allows human placental cytotrophoblasts to develop an invasive phenotype. As altered expression levels of ADAMTS (ADisintegrin And Metalloproteinase with ThromboSpondin repeats) subtypes have been associated with cancer progression, we have examined the function and regulation of members of this gene family in epithelial cell invasion using...

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Identifiers

PMID: 21494557
DOI: 10.1371/journal.pone.0018473
PMCID: PMC3073978

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