Familial scleroderma--evidence for environmental versus genetic trigger.

doi:10.1093/rheumatology/33.12.1131

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Familial scleroderma--evidence for environmental versus genetic trigger.

British journal of rheumatology - 1 Dec 1994

Stephens C O, Briggs D C, Whyte J, Artlett C M, Scherbakov A B, Olsen N, Gusseva N G, McHugh N J, Maddison P J, Welsh K I

Abstract excerpt

Families with more than one case of scleroderma are unusual. Four families each with two members (in one case monozygotic twins) with scleroderma (systemic sclerosis, SSc) were identified. Clinical, immunogenetic and autoantibody studies were carried out. Multicase SSc families cited in the liter...

Topics

Adult
Aged
Alleles
Environment
Family Health
Female
Fluorescent Antibody Technique
HLA-DR Antigens
Humans
Immunoblotting
Immunogenetics
Male
Middle Aged
Pedigree
Scleroderma, Systemic
Severity of Illness Index

Source

Open in PubMed

Identifiers

PMID: 8000741
DOI: 10.1093/rheumatology/33.12.1131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8000741-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics